منابع مشابه
Screening for cystic fibrosis.
Neonatal screening for cystic fibrosis (CF) reduces short-term morbidity but its long term effects remain to be demonstrated. The best available method is the assay of immunoreactive trypsin in dried blood spots, and specificity can be improved by adding direct or indirect genetic analysis. Pregnancies known to be at risk of CF can also be screened by molecular methods, and affected pregnancies...
متن کاملScreening for cystic fibrosis.
Sir, In their Short Report on screening for cystic fibrosis, Vol. 47, pages 131-134, Drs. Cain, Deall, and Noble expressed the hope that their trial would stimulate other maternity units to carry out similar surveys so that the efficiency of the method could be more rapidly assessed. In 1969 we started developing an immunochemical method to analyse meconium for albumin, and since August 1971 we...
متن کاملScreening for cystic fibrosis.
During a 12 month period all New Zealand newborns were screened for cystic fibrosis using the Crossley test. Of 49 056 babies tested 522 had a raised blood immunoreactive trypsin level and follow-up testing indicated 19 persistent elevations. Clinical and laboratory studies indicated 14 cases of cystic fibrosis giving an apparent incidence of 1:3500.
متن کاملNeonatal screening for cystic fibrosis.
Two groups of patients with cystic fibrosis were compared. The screened group, detected with an improved neonatal screening assay for immunoreactive trypsin, developed fewer chest infections requiring treatment and gained more weight than the unscreened group. Early diagnosis by screening seems to affect early morbidity.
متن کاملScreening in cystic fibrosis
A few trials on prenatal CF carrier screening have been performed assessing what proportion of pregnant women are likely to be offered screening and what proportion are likely to accept the test if it is offered free by their own physician (Rowley PT, 1997; Loader S, 1996). A paucity of experience-database is available on CF carrier screening and to terminate CF affected pregnancies. Women foun...
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ژورنال
عنوان ژورنال: Journal of Medical Screening
سال: 1994
ISSN: 0969-1413,1475-5793
DOI: 10.1177/096914139400100214